The US government is investing over $5 billion in the Genesis Mission, which aims to integrate artificial intelligence as a core component in scientific research. This initiative has evolved from a Department of Energy-led effort to a whole-of-government program, focusing on leveraging AI to enhance scientific discovery and tackle national priorities.

US Government: The US federal government directs national policy, research funding, and technological priorities across agencies including the Department of Energy. Under President Trump, it has emphasized AI integration to advance scientific discovery and national competitiveness. In this development, the government is expanding the Genesis Mission into a broader whole-of-government effort with contributions from multiple agencies.
Genesis Mission: Genesis Mission is a national initiative launched via executive order in late 2025 to build integrated AI platforms that harness federal scientific datasets for accelerated discovery. It unites DOE national labs, industry partners, academia, and research infrastructure to apply AI across energy innovation, discovery science, and national security. The program has recently been expanded to incorporate input and resources from additional federal agencies beyond its original DOE lead.

AI Focus: The mission centers on embedding AI as a foundational tool to accelerate scientific research and address national priorities.
Initiative Expansion: The Genesis Mission has moved from a Department of Energy-led effort to a coordinated whole-of-government program.