ClickUp has launched Brain², a comprehensive relaunch of its AI assistant designed to enhance workplace productivity by acting as a context-aware coworker that can operate across the entire workspace. Brain² differentiates itself from general-purpose chatbots by providing users with access to multiple frontier AI models—such as Claude, ChatGPT, and Gemini—under one subscription, each capable of integrating real-time data from a team’s tasks and connected applications. The AI not only retrieves and utilizes this data effectively but also builds custom AI teammates, known as Super Agents, that maintain memory of team preferences, ensuring that users can generate complex deliverables with ease. With a focus on security, ClickUp has also implemented ISO 42001 certification and ensured zero data retention for model training in this new release, positioning Brain² as a strong competitor against offerings from Notion, Slack, and Asana.

Brain²: Brain² is ClickUp’s fully relaunched AI system that functions as a context-aware coworker with access to an entire workspace, including tasks, docs, and connected apps. It dynamically selects and switches among frontier models under one subscription, builds custom Super Agents for ongoing workflows, maintains persistent memory, and ensures responses cite sources while respecting permissions. The system is designed to produce complete deliverables from simple tags or prompts by injecting real-time company context automatically.
ClickUp: ClickUp is a work management platform offering tools for tasks, documents, projects, and team collaboration across desktop and mobile. The company has spent the past two years advancing AI features within its platform and recently launched Brain² to embed context-aware AI directly into users’ workspaces. This release extends ClickUp’s core offering into a model-agnostic AI layer that handles work execution rather than just answering questions.
Qatalog: Qatalog is an enterprise search company whose ActionQuery engine powers retrieval and permission-aware access in AI systems. ClickUp acquired Qatalog along with AI coding startup Codegen specifically to develop and support the retrieval layer for Brain², enabling zero-lag indexing across more than one hundred integrations while maintaining strict data controls.
Zeb Evans: Zeb Evans is the founder and chief executive of ClickUp. He highlighted the limitations of general-purpose AI that lack workspace context and positioned Brain² as a solution that gives any chosen model full access to team data so it can act on work instead of merely describing it.

Competition: ClickUp’s Brain² extends its work-management platform into an AI layer that competes directly with AI offerings from Notion, Slack, and Asana.
AI Integration: Brain² combines multiple frontier models such as Claude, ChatGPT, and Gemini under a single subscription, each with automatic full access to a team’s workspace data from the first prompt.
Security Standards: ClickUp lists ISO 42001 certification and zero data retention for model training as part of the Brain² release.